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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMBRA1 All Species: 7.88
Human Site: T218 Identified Species: 21.67
UniProt: Q9C0C7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C7 NP_060219.2 1298 142507 T218 P E I P I D G T E L S H Y R Q
Chimpanzee Pan troglodytes XP_001163113 1208 132805 A144 N N A I A S L A F H P T A Q L
Rhesus Macaque Macaca mulatta XP_001112256 1298 142465 T218 P E I P I D G T E L S H Y R Q
Dog Lupus familis XP_540754 1211 132916 P147 I A S L A F H P T A Q L L L I
Cat Felis silvestris
Mouse Mus musculus A2AH22 1300 142860 E219 E I P I D G T E L S H Y R Q R
Rat Rattus norvegicus NP_001127813 1300 142989 E219 E I P I D G T E L S H Y R Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233289 1300 142720 T218 V E I S V D S T E M P H Y R Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342016 1003 110813
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797133 781 86047
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.9 99 89.8 N.A. 95.6 95.9 N.A. N.A. 83 N.A. 47.6 N.A. N.A. N.A. N.A. 27.6
Protein Similarity: 100 93 99.3 90.7 N.A. 97.1 97.3 N.A. N.A. 88.9 N.A. 58.7 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 0 100 0 N.A. 0 0 N.A. N.A. 60 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 0 N.A. 20 20 N.A. N.A. 73.3 N.A. 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 23 0 0 12 0 12 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 23 34 0 0 0 0 0 0 0 0 0 % D
% Glu: 23 34 0 0 0 0 0 23 34 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 23 23 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 12 23 34 0 0 0 % H
% Ile: 12 23 34 34 23 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 0 12 0 23 23 0 12 12 12 12 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 12 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 23 0 23 23 0 0 0 12 0 0 23 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 0 0 34 34 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 23 34 23 % R
% Ser: 0 0 12 12 0 12 12 0 0 23 23 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 23 34 12 0 0 12 0 0 0 % T
% Val: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 23 34 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _